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IsraeliDeepTechReport2025

September2025

1Introduction

2TheIsraeliDeepTechEcosystem

3SectorDeepDives

4MethodologyandResources

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Foreword

Theglobaltechindustryisundergoingaprofoundtransformation,shapedbythreemajorforces:ashiftintheglobalinvestmentclimate,markedbyincreasedinvestorcaution;theriseofArtificialIntelligenceandDeepTech,whicharereshapingthestructureandnatureoftheindustry,characterizedbylongtime-to-market,significantcapitalrequirementsandaneedforhighlyskilledtalent;andmassivegovernmentfundingaspartofaglobaltechnologicalarmsrace,withsuperpowersinvestingbillionstodevelopgroundbreakingdeeptechnologies.

IsraelranksamongthegloballeadersinAIandDeepTechinvestmentsandstartupactivitybutmusttakeactiontopreserveitsadvantageamidgrowingcompetition.ThisreportpresentsasnapshotoftheIsraeliDeepTechecosystembutshouldbereadinthecontextoftheseunderlyingtrends,whichinfluencemacroeconomicindicatorsandthefuturedevelopmentoftheindustry.TheimpactofAIisnotyetfullyreflectedinthisedition,butitwillplayasignificantroleinfuturereports.

Since2019,IsraeliDeepTechstartupshaveattractedover$28billionininvestments-representingmorethanone-thirdofallventurecapitalfundinginthecountry.Inthefirst8monthsof2025,DeepTechfundingsurgedto$2.5billionandmaysignalaturningpointafterseveralyearsofdecline.

Israelishometo1,400VC-backedDeepTechstartups,including5AIunicornsand6insemiconductors.IntheWesternworld,IsraelranksfifthforDeepTechfunding,secondonlytoUShubslikeBayArea,Boston,LosAngelesandNewYork,andaheadofLondonandParis.MedicalDevices,Biotech&PharmaandAIarethelargestDeepTechsegmentsinIsraelbynumberofstartupsandfunding.Semiconductors,AI,CybersecurityandMedicalDevicesstartupscreated~$24Binvalueeach.Notably,Israelholdsover20%ofglobalcybersecurityfunding,and9-10%inMedicalDevicesandAgriFood.

Tostrengthenthisleadership,theIsraelInnovationAuthorityisinvestinginearly-stageDeepTechcompaniesthroughthenewlylaunchedStartupFundandislaunchinganewfundoffundstoaugmentspecializedDeepTechVCfunds.Inaddition,theAuthorityfinanceVentureStudiostosupporttheformationandaccelerationofDeepTechventuresinsectorswithlimitedprivatecapitalavailability.

Inaddition,theAuthorityisadvancingnationalprogramsinArtificialIntelligence,Bio-Convergence,QuantumComputing,andClimate,whileinvestinginadvancedtechnologicalinfrastructuressuchasasupercomputerfortraininglargemodelsandlaboratoriesforbio-devicesandbio-chips.

Thesee?orts,combinedwithIsrael?sstrongR&Dfoundationandentrepreneurialspirit,positionthecountryattheforefront,readytoleadthenextwaveofglobalDeepTechinnovation.

Facingglobaltectonicshifts,Israelrequiresadynamicandcreativestrategyandsignificantinvestmentstoaddressthecomplexchallengesofthisera:acceleratinginvestmentsinstrategicdomains,developingadvancedtechnologicalinfrastructures,andcontinuingtonurturetheentrepreneurialecosystemandIsraelihumancapitalacrossallsectors.DeepTechisIsrael?smostimportantnationalresourcetodayandmaintainingitsstatusasagrowthenginerequirescontinuedproactive,coordinated,andstrategicaction.

IwouldliketothankDealroomfortheircollaborationinprovidingdataandinsightsintothisreportandapplaudtheprofessionalismanddedicationofmyteamthroughouttheprocess.

DrorBin

CEO

OtherIIAcontributorstothereport:

EliavOrenbuch

NogaCarmin

Dr.AssafKovo

ChiefEconomist

Dr.LeeRecht

EconomicAnalyst

HeadofTechnologicalResearch

SeniorDirector,HeadofTechnologyandInnovation

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Source:Dealroom.co

KeyTakeaways

Israelranks5thmostDeepTechandLifeSciencesfocusedhubinthe

period2019-2025globally,1stoutsideoftheUS

Since2019,overone-thirdoftotalVCinIsraelhas

consistentlyflowedintoDeepTechandLifeSciences,

drivenmostlybyDeepTech,amountingtoover$28B.Inthatperiod,onaverage370uniqueinvestorsfundedthissegmentyearly.Israelalsoranks5thhubgloballywith$2.9KofDeepTech&LifeSciencesVCinvestment

allocatedpercapitasince2019

Between2017and2024,theshareofIsraeliVCflowingintoDeepTechandLifeScienceswasinoveralldecline.But2025marksapotentialturningpoint,alreadyat

39%,ledbyDeepTechsoftware

VCfundingallocatedinDeepTechandLifeSciences(2019-2025)

$297.3B

BothDeepTechsoftwareandHealth&LifeSciencessoftwarehaveseensignificantgrowthinrecentyears

WhencomparedtoothermajorglobalhubsIsraeldemonstratesahighlydiversifiedtechecosystem,showingstrongcapabilitiesacrossallmajordomains

InDeepTechandLifeSciencessoftware,Enterpriseremainsthemostfundedsector,butSecurity,

Semiconductors,andHealthhavegainedmomentumoverthepastdecade

IsraelisshowingparticularstrengthinAIxDeepTechandMedical

Devices

PrivateIsraeliDeepTechandLifeSciencesstartupsareworthover$112B,upover15xinadecade.Israelcounts39thoroughbreds&/orunicornsinthissector

AI,MedicalDevices,andBiotech&PharmahavethelargestpoolofVC-backedcompanies,withAIandMedicalDevicesalsoraisingthemostfundinginrecentyears.2025hasbeenastandoutyearforAIandQuantumVCactivity

CybersecurityisinsteadthesegmentwhereIsraelclaimsthelargestshareofglobalfundingwithover20%,followedbyMedicalDevicesandAgriFoodat9-10%

VCinvestmentinIsraeliDeepTechandLifeSciencesstartupsbytechnology

Numberofstartups,valuecreatedandVCfundinginselectedDeepTechsegmentsinIsrael

DeepTechdefined

DeepTechistechnologythatisbasedontangibleengineering

innovationorscientificadvancesanddiscoveriesappliedforthefirsttimeasaproduct,oftenaimingtosolvesociety?sbiggestissues

Practically,acompanyisconsideredDeepTechbasedon

Primarycriteria

Timetomarket/Complexity:Thecompanyisworkingwithatechnologythattakesalongtimetoreachmarket-readymaturityduetothe

complexityandnoveltyoftheresearchanddevelopmentinvolved.Itthusemploysalotofhighlyeducatedsta?earlyonandmaycreatenovelhardwareorintellectualproperties

Capitalrequirement:Thecompany?stechnologyshouldrequire

substantialinvestmenttofundtheresearch,development,testing,andscalingoftheproductorservice

Secondarycriteria

IPandspinouts:companiesholdingsignificantIPandcommercializingresearchinnovationsaremorelikelytobeDeepTech

Di?erencesinriskprofileDeepTechvsRegularTechstartups

Developmenttimes

Longerinitialdevelopmentphase

Capexintensity

OftenheavyCapExaheadofrevenuesandPMF

Marketrisk

Ifthetechnologycanmeetcostandperformancemetricsthere?softenvalidateddemand

DeepTech

Regular

Tech

Teamrisk

Academicandscientific

backgroundsmayhavelesscommercialexperience

Competitionrisk

Oftenthestrongtechnologyedgecreatesastrongmoatforcompetition

Technologyrisk

Newtechnologiesdon?talwaysworkasexpected

Scopeofthisreport:Inthisreport,weexploreinnovationsinDeepTech,asdefinedabove,aswellasintheLifeSciencessector

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Source:The2025EuropeanDeepTechReportbyDealroom,Lakestar,WaldenCatalystandHelloTomorrowExamplesofwhichstartupsegmentsareconsideredDeepTechornotbysectorcanbefoundintheappendix

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DeepTechandLifeSciences

Inthisreport,weexploreinnovationsinDeepTech,aswellasintheLifeSciencessector.StartupsattheintersectionofDeepTechandLifeSciences(e.g.AIdrugdiscovery,TechBioetc.)arecountedwithinLifeSciences

LifeSciencesdefinition

Startupsin(Health)LifeSciences,alsocommonlyreferredtoasBiotechandPharma,focusondevelopingnewdrugsandtherapiesbasedonchemicalprocessesorderivedfromlivingorganismstoimprovehumanhealth.

Thisalsoincludescompanieswhoseprimaryfocusissoftwareand

hardwareproductsfortheLifeSciencessector,suchasbioreactors,cell

culturetech,proteomicsandsequencing,orAI-drugdiscovery.These

DeepTech*

Companiesbasedontangibleengineeringinnovationor

companies,sometimesreferredtoasTechBio,areoftenconsideredtobebothLifeSciencesandDeepTech;inthisreport,theyareassignedtoLifeSciencestoavoidoverlaps

scientificadvancesand

discoveriesappliedforthefirst

timeasaproduct,oftenaiming

tosolvesociety?sbiggestissues

LifeSciences

Companiesdevelopingnewdrugsandtherapiesbasedonchemical processesorderivedfromlivingorganisms.Italsoincludesspecificsoftwareandhardwareforbiotechandpharmalikebioreactors,cellculturestech,orAI-drugdiscovery

ItdoesnotincludeHealthsectorssuchasMedicalDevices(deviceintendedtobeusedformedicalpurposesandsubjectedtoregulatoryapproval)andDigitalTherapeutics(evidence-basedtherapeuticinterventionsdrivenbysoftwaretoprevent,manage,ortreatamedicaldisorderordisease),whichareinsteadincludedinDeepTechiftheyfitthecriteriaoftimetomarket,

complexity,capitalrequirementandresearch-intensiveness

(e.g.space,semiconductors,

nuclear,quantumand

photonics,batteries,…)

Itdoesnotincludebiotechapplicationsinsectorsbeyondhealth,suchasagritechandfoodtech(e.g.cropengineering,cultivatedmeat,precision

fermentation),chemicalsandmaterials(e.g.biomaterialsand

biomanufacturing)andothers.ThosebiotechcompaniesareincludedinDeepTechiftheymeetthecriteriaoftimetomarket,complexity,capitalrequirements,andresearchintensity

ItdoesnotincludemostdigitalhealthplatformsforexampleElectronicHealthRecordssoftwaresorotherorganizationalSaaSforhospitalsandpractitioners,thesearenotconsideredDeepTecheither

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Source:The2025EuropeanDeepTechReportbyDealroom,Lakestar,WaldenCatalystandHelloTomorrow*ExamplesofwhichstartupsegmentsareconsideredDeepTechornotbysectorcanbefoundintheappendix

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GeographicalScope

Israela?iliatedstartups

ssi

VElos

Topic

nanit

IsraelHQStartups

Startupswiththeirmainbusinesscenter(HQ)basedintheregion

1.3K

+activeDeepTechandLifeSciencesVC-backedstartups

AlephFarms!

CLASSIQ

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Israel-foundedstartups

Startupsoriginatingintheregion,whichmovedtheirmainplaceofbusinesselsewhereastheyscaled

1.4K+activeDeepTechandLifeSciencesVC-backedstartups

-including100+relocatedcompanies

Scopeoftheanalysis

Source:Dealroom.co

Israelistartupsaredefinedascompaniesthateither:

●havetheirheadquartersinIsraelandmaintainasignificantpresenceinthecountry,or

●wereoriginallyfoundedinIsrael,eveniftheyhavesincerelocatedtheirheadquartersabroad

Thenationalityofthefoundersandtheoriginofthe

underlyingtechnologyarenotconsidereddeterminingfactorsbythemselves.StartupsfoundedbyIsraeli

nationalsentirelyabroad,withlittleoperationalor

historicaltiestoIsrael,areexcludedfromthisanalysis

Startupsfoundedandscaledabroad,with(co-)foundersfrom,and/orintellectualpropertygrown,and/orfundingsecuredin,theregion

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1Introduction

2TheIsraeliDeepTechEcosystem

3SectorDeepDives

4MethodologyandResources

Page/9

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Source:

OECDDataexplorer

IsraelleadstheworldinR&Dintensity,investing6.2%ofitsGDP,drivenlargelybyitsdynamicprivatesectorandstrongforeigninvestment

R&Dintensityforselectedeconomiesperfundingsource,OECD2022

▊Localbusinesssector▊Government▊HighereducationandPNPsectors▊Foreigninvestors

Israel

Outcomestodate

TheIsraelitechecosystemhas1.4K+VC-backedstartupsinDeepTechandLifeSciences,andalreadycreated39companieswith$100M+revenuesand/or$1B+valuation

Flowofnewstartups

52

Colts

($25-100Mrevenue)

39

Thoroughbredsand/or

Unicorns

($100M+revenue);($1B+value)

40+

startups

raisetheirfirst

VCroundeach

year

since2019

%ofallIsraelistartups-allsectorsincluded

994

Startups

(<$15Mfunding)

369

Breakouts($15–100M funding)

121

Scaleups($100M+funding)

23%

38%

46%

25%30%

Poolof±1.4KVC-backedDeepTechandLifeSciencescompaniesHQorfoundedinIsrael

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Source:Dealroom.co;IncludesstartupsHQ?dorfoundedinIsrael;excludesclosedstartups.Startupstageincludesstartupswithundisclosedfunding.Pre-fundingstartupsincludeonlythosefoundedsince2019,withnotableactivityandnopubliclydisclosedround

IsraeliDeepTechandLifeSciencesstartupshave

raisedover$28Bsince2019,morethananyselectedhuboutsidetheUS(London,

Switzerland,Paris,…)

Israeliscloselyfollowedby

LondoninDeepTech&Life

SciencesVCfundingsince

2019,thoughLondonremainsslightlyaheadin2025sofar

DeepTechandLifeSciencesVCinvestment,byselectedhubs(2019-2025and2025)

$81.2B

$297.3B

5TH

7TH

Source:Dealroomco;BayAreaincludes$40BraisedbyOpenAIinMarch2025.Selectedhubsshown

.

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basedonrelevanceforcomparisontoIsrael.Notanexhaustivelist(e.g.Austinnotincluded)

2025dataasofSeptember2025.

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Source:Dealroom.co;SelectedhubsshownbasedonrelevanceforcomparisontoIsrael.Notanexhaustivelist(e.g.Austinnotincluded)

Israelisalsoa

leadinghubin

DeepTech&LifeSciencesVCper

capita,with$2.9KVCinvestment

raisedperinhabitant

Israelranks5thpercapita,

followingBayAreaand

BostonintheUSand

StockholmandMunichin

Europe,aheadofLosAngelesandLondon

DeepTechandLifeSciencesVCinvestmentpercapita,byselectedhubs(2019-2025)

$36.8K

$16.1K

5TH

Israelranks4thinDeepTechandinHealth&LifeSciencesamongselectedhubs

VCinvestmentinDeepTech(exc.Health&LifeSciences)(2019-2025)

VCinvestmentinHealth&LifeSciences(2019-2025)

$0.86B

$0.65B

Source:DealroomStartupsattheintersectionofDeepTechandLifeSciences(eAIdrugdiscovery,TechBioetc)welldeeptechhealthsolutionsrobotic

.co..g..asaspuree.g.

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MedicalDevicesarecountedwithinHealth&LifeSciences.BayAreaincludes$40BraisedbyOpenAIinMarch2025.SelectedhubsshownbasedonrelevanceforcomparisontoIsrael.Notanexhaustivelist(e.g.Austinnotincluded)

GlobalVCisincreasinglyfocusedonDeepTechandLifeSciences.DeepTechisleading,withsomeexceptionssuchasBostonandSwitzerland

ShareoftotalVCfundingallocatedinDeepTechandLifeSciences

▊DeepTech(exc.Health&LifeSciences)▊Health&LifeSciences

2019-20252025

Source:DealroomStartupsattheintersectionofDeepTechandLifeSciences(eAIdrugdiscovery,TechBioetc)wellDeepTechhealthsolutionsrobotic

.co..g..asaspuree.g.

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medicaldevicesarecountedwithinHealth&LifeSciences.BayAreaincludes$40BraisedbyOpenAIinMarch2025andwouldbe54%withoutit.Totalsmaynotaddupduetorounding.SelectedhubsshownbasedonrelevanceforcomparisontoIsrael.Notanexhaustivelist(e.g.Austinnotincluded.2025dataasofSeptember2025.

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2025isshowing

renewedinterestinIsraeliDeepTechwithover$2.5B

alreadyraised,matchingthewholeof2024

AtthispaceDeepTechVC

fundinginIsraelwouldgrow28%sincelastyearandreachbackpre-pandemiclevels,

butstillshortof2021/2022

Roughly$25B(70%ofVC)

since2015wasraisedby

1.3K+startupsstillHQin

Israel;$11B(30%)wasraisedby100+thatmovedtheirHQabroad,mainlytotheUS

VCinvestmentandnumberofroundsinIsraeliDeepTechandLifeSciencesstartups

?viewonline

▊$0–1m(pre-seed)▊$1–4m(seed)▊$4–15m(seriesA)▊$15–40m(seriesB)▊$40–100m(seriesC)▊$100–250m(megarounds)▊$250m+(mega+)▊Projection

NumberofRounds

VCinvestment

$2.5B

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Source:Dealroom.co;VCinvestmentandnumberofroundsprojectedasofSeptember2025.Recentyears(especially2023–2025)mayshowfewerroundsduetoreportinglag,particularlyatearly

stages,astheyareoftendisclosedlater

2025dataasofSeptember2025.

TopDeepTechandLifeSciencesroundsinIsraelin2024-2025

Software

NWEKA

$140MSeriesEMay2024

CLASSIQ

$110MSeriesCMay2025

$300MSeriesDMay2025

silverfort

$116MSeriesDJan2024

$100MSeriesBAug2025

$100MSeriesBFeb2025

Hardware/Software

$170MSeriesCFeb2025

vexodigo

$96MSeriesBJul2025

$80MGrowthEquityVCJul2024

Hardware

$136MLateVCFeb2024

$150MLateVCJun2024

$125MSeriesBJun2025

$105MLateVCJul2024

Bionx

$50MPrivate

placementVC

Mar2024

$68MSeriesDOct2024

Software

aldcc

$110MLateVCJul2025

區health

$50MLateVCJul2024

$80MSeriesBJul2024

$50MSeriesAMay2025

sensi.AI

$31MSeriesB$20.3MEarlyVC

Jun2024May2025

DeepTechHealth&LifeSciences

Hardware

Rehyn

$75MSeriesDMar2025

$120MSeriesCApr2024

$75MSeriesFFeb2025

@"oeewse

$50MSeriesBJun2025

$74MSeriesBApr2024

$50MSeriesAJul2025

?Viewonline

?Viewonline

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Source:Dealroom.co

*Health&LifeScienceshardwareincludesMedicalDevicesbutalsodrugmanufacturing

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Since2015,over

one-thirdoftotalVCinIsraelhas

consistentlyflowedintoDeepTechandLifeSciences,

drivenmostlybyDeepTech

Between2017and2024,theshareofIsraeliVCflowingintoDeepTechandLifeScienceswasinoveralldecline.

But2025marksapotential

turningpoint,witha39%

shareofthefundingsofar

thisyear,ledbyDeepTech

beyondHealth&LifeSciences

ShareofDeepTechandLifeSciencesintotalIsraeliVCfunding

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Source:Dealroom.co;StartupsattheintersectionofDeepTechandLifeSciences(e.g.AIdrugdiscovery,TechBioetc.)arecountedwithinLifeSciences.

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Source:Dealroom.co;StartupsattheintersectionofDeepTechandLifeSciences(e.g.AIdrugdiscovery,TechBioetc.)arecountedwithinLifeSciences.

DeepTechsoftwareandHealth&LifeSciencessoftwarehaveseen

significantgrowthinrecentyears,

makingup41%ofthesectorsince2019

VentureCapitalinvestmentinIsraeliDeepTechandLifeSciencesstartupsbytechnology

E.g.FoundationalAImodels,novelcybersecurity,cryptoinfrastructure

Since2019:

-HealthandLifeScienceshaveattracted34%oftotalfunding,with25%allocatedtohardwareand9%tosoftware.

-DeepTechHardwarereceived26%,whilehardware-enabledsoftwareaccountedfor8%.

-PureDeepTechsoftware

attracted32%andnowmakesupthemajorityofdeeptechfunding.

E.g.quantumcomputing,AR/VR

E.g.semiconductors,batteries

E.g.drugdiscoveryplatforms

E.g.surgicalrobotics,diagnosticsdevices,drugmanufacturing

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Source:Dealroom.co;*Securityincludescyberandhomelandsecurity

Withinsoftware

TechandLife

Sciences,

Enterprise

softwareremainsthemostfundedindustrybutothersectorslike

Security,

Semiconductors

andHealthhave

startupsinDeepVentureCapitalinvestmentinIsraeliDeepTechandLifeSciencesSaaSstartupsbyindustry

beenrampingupinthepastdecade

Healthoutstandingyearin2023,Securityin2020andSemiconductors/quantumstronggrowththisyear

E.g.transportation(avsoftware),

fintech(blockchain),food(farmingandirrigationtool)etc.

E.g.cloudservices,aimodels

*

E.g.cybersecurity,facialrecognition

E.g.quantumcomputingsoftware,lidarsoftware

E.g.healthassistant,imagingsoftware

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Source:Dealroom.co

Israelhasahighlydiversifiedtech

ecosystem,

showingstrong

capabilitiesacrossallmajordomains,inlinewithParisandLondon

Incontrast,theBayArea

showsaverystrong

orientationtoDeepTech

Software(e.g.foundationalAImodels),andNewYorkandSingaporetowardsHealth&LifeSciences

ComparisonofDeepTechandLifeSciencesVCfundingbyhubs(2019-2025)

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dealroom.co

Source:Dealroom.co

2025dataasofSeptember2025.

PrivateIsraeliDeepTechandLifeSciences

startupsare

worthover

$112B,upmorethan16xina

decade

66%ofthevaluehasbeen

createdbystartupsborninthelast10years.When

consideringalsoexited

companies,IsraeliDeepTechandLifeSciencesstartups

havegeneratedmorethan

$178B

inenterprisevalue

CombinedenterprisevalueofprivateIsraeliDeepTechandLifeSciencesVC-backedstartups

?viewonline

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dealroom.co

Source:Dealroom.co;AnalysiscoversstartupsHQandfoundedinIsrael.Excludesundisclosedinvestors.Whenmultipleinvestorsparticipateinaround,amountinvestedisequallydividedbetweentheco-participants.*ExcludesDeepTechandLifeSciences

IsraeliDeepTechstartupsraisemostoftheirfundingfromforeigninvestors,withdomesticinvestmentrangingfrom~35%attheearlystageto~15%atlatestage,broadlyalignedwiththerestoftheIsraeliecosystem

VCinvestmentbyIsraeliDeepTechandLifeSciencesstartups(2023-2025)

VCinvestmentbyotherIsraelistartups*(2023-2025)

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Source:Dealroom.co;AnalysiscoversstartupsHQandfoundedinIsrael.Excludesundisclosedinvestors

ForeigncapitalplaysabiggerroleinIsraelDeepTechandLifeSciencesatallstagescomparedtootherkeyleadinghubs

VCinvestmentbydomesticinvestorsintoDeepTechandLifeSciencesstartups(2023-2025)

TopinvestorsinIsraeliDeepTechandLifeSciences

?viewonline

(Pre-)Seed

IsraeliInvestors

InternationalInvestors

SeriesA

Johnson&Johnson

SquarePegCap.

SeriesB+

Source:Dealroomco;Domesticfundsselectedbasedonnumberofroundssince2019(minimum10publiclydisclosedroundssince2019)or

.

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shareofDeepTechandLifeSciencesinvestmentinglobaltotal(min50%,morethanfiverounds).Investorsareshownonlyatthemostcommonentrystagepoint.Onlylookingatdirectinvestmentactivity,notLPactivityinfunds

Foreign

investors

continuetoleadfundingactivityinIsraeli

DeepTechandLifeSciences

Israeliinvestorsareaboutaquarteroftheoveralldeeptechinvestors

NumberofuniqueinvestorsinIsraeliDeepTechandLifeSciencesstartups

Source:DealroomIfinvestorhasatleastinvestmentintheitiscountedforthatRecent

.co;anoneyear,onceyears(especially2023–2025)mayshowfewerinvestors/roundsduetoreportinglag.Includesandcorporates,butnotangelsoraccelerators.ProjectionasofAugust2025.

year.

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investmentfunds

ExitactivityinbothDeepTechandLifeScienceshas

slowedinrecentyears

Bytheendof2025,thetotalnumberofexitsisprojectedtobejust?ofthe2021peak

HealthandLifeSciencesexits

haveremainedrelativelystableoverthepastdecade,showinglittlefluctuation.Incontrast,

DeepTechexperiencedasurgebetween2019and2022andthendeclined

Still,in2025,thenumberofDeepTechexitsexceedsthatofHealthandLifeSciences

NumberofVC-backedIsraeliDeepTechandLifeSciencespublicandprivateexitspertechnology

▊Health&LifeSciencesHardware▊Health&LifeSciencesSoftware▊DeepTechHardware

▊DeepTechHardware/software▊DeepTechSoftware▊Others▊Projection

Source:Dealroomco;StartupsattheintersectionofDeepTechandLifeSciences(egAIdrug

.

..

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dealroom.co

discovery,TechBioetc.)arecountedwithinLifeSciences.

2025dataasofSeptember2025.

Mostoftheexitvaluecreated

stemsfromDeepTechstartups

2021wasastandoutyear,drivenby

SentinelOne

?s$8.9BIPObutnotonly,

20+

otherstartupsreached

+$100Mexits

AlthoughHealth&Life

SciencesmakeuphalfofDT&LSexitcount,theyhave

historicallyrepresentedonlyasmallfractionwhen

measuredbyvolume.Thisyear,theysurpassdeeptech

ValueofIsraeliDeepTechandLifeSciencesVC-backedexits(M&AsandIPOs)

Source:Dealroomco;StartupsattheintersectionofDeepTechandLifeSciences(egAIdrug

Projection

DeepTech

Health&LifeSciences

.

..

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discovery,TechBioetc.)arecountedwithinLifeSciences.

2025dataasofSeptember2025.

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Source:Dealroom.co

Largestexitsin2024-2025byvaluation

ExitsofIsraeliDeepTech&LifeSciencesstartups,knownexitvaluation>$100M(2024-2025)

?viewonline

CompanyAcquirorsExitroundSegment

Run:AI

ION@iware:AIcomputing

$600mACQUISITION@$600maug/2024

Johnson&Johnson

V-Wave

Akarmnai

$450mACQUISITION@$450mmay/2024

Health&LifeScienceshardware:Medicaldeviceforheartfailure

Noname

Security

DeepTechsoftware:Cybersecurityplatform

$360mACQUISITION@$400mmar/2025

SoniVie

Health&LifeScienceshardware:intravascularultrasoundsystem

$75mIPO@$244mjun/2024

$144mSPACI

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